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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCA1
All Species:
1.21
Human Site:
T1555
Identified Species:
2.42
UniProt:
O95477
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95477
NP_005493.2
2261
254286
T1555
S
Q
E
V
N
D
A
T
K
Q
M
K
K
H
L
Chimpanzee
Pan troglodytes
XP_001138040
2261
254230
I1555
S
Q
E
V
N
D
A
I
K
Q
M
K
K
H
L
Rhesus Macaque
Macaca mulatta
XP_001106713
1081
120445
W472
Q
Q
F
V
A
L
L
W
K
R
L
L
I
A
R
Dog
Lupus familis
XP_538773
2261
253895
I1555
S
Q
E
V
N
N
A
I
K
Q
V
K
K
H
L
Cat
Felis silvestris
Mouse
Mus musculus
P41233
2261
253955
I1555
S
H
E
V
N
D
A
I
K
Q
M
K
K
L
L
Rat
Rattus norvegicus
Q7TNJ2
2170
237702
V1509
N
K
G
W
H
A
M
V
A
F
V
N
R
A
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516009
2266
254238
I1560
S
D
E
V
S
D
A
I
K
Q
V
K
K
L
F
Chicken
Gallus gallus
NP_989476
2260
254054
I1554
S
N
E
V
T
D
A
I
K
Q
V
K
K
I
L
Frog
Xenopus laevis
NP_001089022
2363
267334
F1659
E
G
D
I
I
S
F
F
S
H
L
G
K
M
T
Zebra Danio
Brachydanio rerio
XP_683123
2330
265308
F1622
P
E
E
I
Q
N
I
F
S
Q
L
G
R
M
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34358
1704
191394
V1096
R
A
R
L
T
G
T
V
D
A
E
I
S
S
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84M24
1882
209045
T1274
G
L
A
I
A
S
S
T
Y
C
L
T
F
F
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
47
94.9
N.A.
95
50.8
N.A.
89.1
85.4
49.8
51.1
N.A.
N.A.
N.A.
24.9
N.A.
Protein Similarity:
100
99.7
47.5
97.6
N.A.
97.3
67.4
N.A.
94.6
92.6
66.8
67.8
N.A.
N.A.
N.A.
43
N.A.
P-Site Identity:
100
93.3
20
80
N.A.
80
0
N.A.
60
66.6
6.6
13.3
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
93.3
33.3
93.3
N.A.
80
33.3
N.A.
73.3
73.3
26.6
53.3
N.A.
N.A.
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
9
0
17
9
50
0
9
9
0
0
0
17
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% C
% Asp:
0
9
9
0
0
42
0
0
9
0
0
0
0
0
0
% D
% Glu:
9
9
59
0
0
0
0
0
0
0
9
0
0
0
0
% E
% Phe:
0
0
9
0
0
0
9
17
0
9
0
0
9
9
17
% F
% Gly:
9
9
9
0
0
9
0
0
0
0
0
17
0
0
9
% G
% His:
0
9
0
0
9
0
0
0
0
9
0
0
0
25
0
% H
% Ile:
0
0
0
25
9
0
9
42
0
0
0
9
9
9
0
% I
% Lys:
0
9
0
0
0
0
0
0
59
0
0
50
59
0
0
% K
% Leu:
0
9
0
9
0
9
9
0
0
0
34
9
0
17
42
% L
% Met:
0
0
0
0
0
0
9
0
0
0
25
0
0
17
9
% M
% Asn:
9
9
0
0
34
17
0
0
0
0
0
9
0
0
9
% N
% Pro:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
9
34
0
0
9
0
0
0
0
59
0
0
0
0
0
% Q
% Arg:
9
0
9
0
0
0
0
0
0
9
0
0
17
0
9
% R
% Ser:
50
0
0
0
9
17
9
0
17
0
0
0
9
9
0
% S
% Thr:
0
0
0
0
17
0
9
17
0
0
0
9
0
0
9
% T
% Val:
0
0
0
59
0
0
0
17
0
0
34
0
0
0
0
% V
% Trp:
0
0
0
9
0
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _